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Molar Pregnancy (181344)
Molar Pregnancy new
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munafdesai
2007-03-20 04:56
Histopathology Forum
f/35yrs, product of conception, ? molar pregnancy, S beta HCG not known.  
 
Hydropic swelling or partial mole?  
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jclaro
2007-03-20 10:40
Dr Munaf, in image number 4, seems to me, consistent with vesicular villi, associated in antohers images, with hidropic villi and endometrial tissue. In my point of view, partial mole.
ugnius
2007-03-20 11:04
Gestation (8-12) weeks (erythroblasts in vilous vessels): degenerative changes (fibrosis). Focal edema, eccentric/usual proliferation of the trophoblast.
gmlearmonth
2007-03-21 12:00
As I am not very familiar with the finer points of trophoblastic pathology I suggest referral of this case to a gynaecological pathologist.
sdas
2007-03-21 16:17
I agree with Dr Claro.
sachin
2007-03-22 04:50
I am not an expert but this does not appear to be mole to me. If you want conclusively rule out partial mole from hydropic abortus Ki67 or ploidy studies may be done.  
Which trimester products, is an important cnsideration.  
Check out these things -  
http://www.ihcworld.com/_newsletter/2003/focus_mar_2003.pdf  
http://www.springerlink.com/content/mja64bn8rag850ar/fulltext.pdf  
I would be interested to know how you will sign this out.
jclaro
2007-03-22 11:08
Dr Sachin, interesting review, thanks.
kunze
2007-03-22 12:49
The irregularly shaped medium- to large-sized villi with focal invagination of trophoblast cells and some scattered hydropic villi are characteristics of an embryonal mole but not of a partial or complete hydatidiform mole.
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Last modified: 2007-03-20 04:56:21